RNA biology and biochemistry studies have become a hotspot in basic and translational research. This is because RNA is not only a bridge between the genetic code and proteins, but it is also a key regulator of gene expression at multiple levels. Being that a key regulator makes various types of RNA molecules responsible for … Continue reading RNA 3D Structure Prediction: Importance, Challenges, and Advances
The Synthetic Yeast Genome Project - Sc2.0 is a state-of-the-art initiative in which scientists from all around the world are collaborating to synthesize an entire eukaryotic genome, specifically that of Saccharomyces cerevisiae. This endeavor aims to empower researchers to understand and overcome obstacles in genome improvement, fostering the creation of more robust organisms for key … Continue reading An Entirely New tRNA Chromosome: Are we truly on the brink of synthesizing new forms of life?
An increasing knowledge concerning the genetic code helped us to better understand the mechanisms of translation. Now being a text-book knowledge, the genetic code is made up of 64 codons, of which 61 code for amino acids and three for stop codons. Corresponding number of tRNAs is needed for pairing with complementary triplets in mRNA … Continue reading Codon Reassignment: Breaking the Rules of Genetic Language
Gene expression is intricately controlled through various regulatory layers, spanning from transcription to post-translational modifications. In 1970, the discovery of RNA editing marked a pivotal moment in molecular biology, unveiling N6-methyladenosine (m6A) as the first identified RNA modification. Today, RNA editing stands as a crucial facet of gene regulation, contributing not only to our understanding … Continue reading From RNA Editing to Nobel Honors: Revolutionizing RNA Based Therapeutics
Gene silencing is an extremely important phenomenon occurring within cells to control processes such as homeostasis and development. This is achieved through the alteration of gene expression patterns via various mechanisms. The significant advancements in molecular biology have placed considerable pressure on the development of gene silencing techniques to study gene function and regulation and … Continue reading RNA Interference: A Leap In Molecular Biology
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