When you see two teams you don't know playing a sport or watch a movie for the first time, you will often take sides and cheer for a specific team or character to win. Taking sides is a fundamental human trait. Of course, we are not here to discuss psychology or social sciences. Instead, I … Continue reading Taking Sides in Science: A Path to Progress or Pitfall?
Nucleic acids and proteins are the backbone of most biological processes within the cell. The flow of information from DNA to messenger RNA (mRNA) and then to proteins defines the central dogma of molecular biology. Transcription involves generating mRNA from a DNA sequence, transferring information from one nucleic acid molecule to another. The subsequent step, … Continue reading Non-Canonical Roles of tRNA: tRNAs in the Dynamic Soup of the Cell
RNA biology has won two consecutive Nobel Prizes in 2023 and 2024. Along with other groundbreaking discoveries, these Nobel Prize-winning advancements in RNA biology have significantly impacted the field of molecular biology and continue to challenge some of our central ideas about life and gene regulation. One of the best examples supporting this notion is … Continue reading The Evolution of the Central Dogma: Insights from RNA Biology
If you put any cell under the microscopy, with some fluorescent proteins and RNAs, you will see it light up with mesmerizing constellations. Just like oil droplets in water, they find each other forming a sort of mini environment amid all the crowded cellular space. A long standing problem in the field of cell biology … Continue reading Biomolecular condensates: more than just a phase
Supervising a PhD student is a weighty responsibility that plays a pivotal role in preparing and shaping the next generation of scholars and researchers. A PhD supervisor guides the student through their doctoral studies, ensuring that they are equipped with the knowledge, skills, and resources needed to succeed in their future endeavors in academia. At … Continue reading Hands-On vs. Hands-Off: Finding the Right Approach in PhD Supervision
Macromolecules' stability governs and affects most cellular processes, well-being, and the life cycle. Beyond the cellular level, it plays a key role in development, physiological responses, and homeostasis. The two sister nucleic acids, RNA and DNA, share many similarities, but they differ greatly in their respective half-lives. DNA is an extremely stable molecule that can … Continue reading RNA Stability: From Transient Messengers to Resilient Architects
RNA biology and biochemistry studies have become a hotspot in basic and translational research. This is because RNA is not only a bridge between the genetic code and proteins, but it is also a key regulator of gene expression at multiple levels. Being that a key regulator makes various types of RNA molecules responsible for … Continue reading RNA 3D Structure Prediction: Importance, Challenges, and Advances
RNA Stuff 