Non-Canonical Roles of tRNA: tRNAs in the Dynamic Soup of the Cell

Nucleic acids and proteins are the backbone of most biological processes within the cell. The flow of information from DNA to messenger RNA (mRNA) and then to proteins defines the central dogma of molecular biology. Transcription involves generating mRNA from a DNA sequence, transferring information from one nucleic acid molecule to another. The subsequent step, … Continue reading Non-Canonical Roles of tRNA: tRNAs in the Dynamic Soup of the Cell

Codon Reassignment: Breaking the Rules of Genetic Language

An increasing knowledge concerning the genetic code helped us to better understand the mechanisms of translation. Now being a text-book knowledge, the genetic code is made up of 64 codons, of which 61 code for amino acids and three for stop codons. Corresponding number of tRNAs is needed for pairing with complementary triplets in mRNA … Continue reading Codon Reassignment: Breaking the Rules of Genetic Language