A recent Science paper described an extremely strange antiphage reverse transcriptase system, DRT3. DRT3 is made up of two RT-like proteins, DRT3a and DRT3b, and a non-coding RNA. These assemble into a large ribonucleoprotein complex with six copies of each component. Functionally, the two RTs make opposite strands of an alternating dinucleotide DNA repeat. DRT3a … Continue reading DRT3 and the Creativity of Molecular Biology